‘diabetes mellitus’

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Diabetes Mellitus is The Leading Cause of Death

Thursday, July 22nd, 2010

diabetes mellitus

For over 10 years, diabetes is among the five leading causes of death in the IMSS, Chihuahua, childhood obesity being the main trigger factor of this disease in children 10-17 years of age as at puberty and adolescence, hormonal changes occur that involve alterations in the levels of insulin in the body, so the more likely that children and young people suffering from diabetes mellitus.

Another major cause of diabetes mellitus in youth are poor eating habits and lack of exercise.

Diabetes mellitus is a disease that can occur at any age, both hereditary and environmental factors, is an incurable disease, but can be controlled. This brings suffering in the short and long term, ranging from vision problems, blood circulation, heart disease and may reach renal failure.

Most likely to have diabetes mellitus are the group of adults over 60 years of age. Some symptoms that present themselves are: weakness, fatigue and increased urination.

(more…)

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The Most Important Advances For Treating Diabetes

Wednesday, May 19th, 2010

Diabetes MellitusA little less than a year, Exubera was approved by the FDA (Food and Drug Administration or the United States Food and Drug Administration) for the treatment of type 1 diabetes and in some cases of type 2 diabetes.

The big challenge was that, until recently, scientific evidence showed that the only way of administering insulin was skin, however, found that it can be absorbed by the blood without needles or syringes, using a inhaler similar to that used in treating asthma. With the approval of this drug makes a pattern in the treatment of diabetes mellitus. (more…)

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Diabetes Mellitus

Monday, March 29th, 2010

Diabetes mellitus is a disease with significant morbidity and mortality, so that its effects were studied in relation to the various organs it affects reproductive function without exception. To achieve this, it has resorted to using various animals as experimental models to which they are induced diabetes. Various substances have been reported to induce diabetes in animals, being estretptozotocina (STZ) which has shown greater effectiveness. The STZ is an antibiotic produced by Streptomyces achromogenes, which has selectivity for the pancreatic beta cells, destroying them through DNA fragmentation. It has been shown that STZ diluted in buffer, stabilized for about two hours and stored at 6 º C, has a diabetes-inducing capacity, especially in species such as rats, mice and hamsters. In rats with diabetes induced reproductive abnormalities have been associated with alterations in the hypothalamic-pituitary-gonad, both by decreased secretion of GnRH, as deficient secretion of LH, FSH and prolactin, as well as alterations in the gonadal and production of steroid hormones (testosterone, estrogen and progesterone). This results in male rats, reduced sperm production and the decrease in their mobility. For females, the main changes are greedy atrophy, abnormal folliculogenesis, corpus luteum insufficiency, uterine involution and problems associated with the maintenance of pregnancy. In several studies have found the prevalence of birth defects in the products of rats with STZ-induced diabetes, the most frecuetnes developmental delay, abnormal neural tube closure, cardiac abnormalities and micrognathia, among others.

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Test For Gestational Diabetes

Saturday, March 27th, 2010

What to Know, A majority of women who underwent a test for gestational diabetes between weeks 24 and 28 of pregnancy or earlier if you are at risk.

If you have gestational diabetes, you may be able to control it through diet and exercise. Your doctor may recommend that controls the level of blood sugar regularly at home. You can do it with a special needle test meter or blood sugar. Some women with gestational diabetes need insulin injections.

Gestational diabetes usually disappears after delivery, but women who develop it are at risk of developing it again in a future pregnancy, or diabetes in the future. Exercising, eating a diet low in sugar and losing weight can help lower your risk of developing diabetes in the future

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Diabetes & Pregnancy

Tuesday, March 9th, 2010

The screening is based on fasting glucose in the laboratory, except during pregnancy when a particular test is necessary. There is no French recommendations on screening procedures, but the U.S. ADA (American Diabetes Association) recommends screening every three years:

  • in people 20 to 44 with high weight and sedentary
  • in people 45 to 64 with a high weight or sedentary
  • among those over 65 with high weight, or a first degree relative with type 2 diabetes or in women who have given birth to a baby weighing over 4 kg.

These criteria selected 31% of the general population in which screening would be more likely to be positive, which would be a big saving compared to routine screening in all individuals, but the sensitivity of these criteria would be only 79 %, which means that 21% of diabetics true escape nonetheless screening. However, diabetics who are not obese or sedentary probably have less cardiovascular risk.

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recommendations for nutrition and type 1 diabetes in pregnancy/
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Cases of Diabetes

Sunday, March 7th, 2010

In the absence of screening and repeated throughout the population, it appears logical to be screened individuals at greatest risk:

  • families where there are known cases of diabetes (about 80% of diabetics have type 2 diabetes heredity known or unknown)
  • male or female, who were overweight, defined by a BMI over 25 (just over 50% of men and 70% of women with type 2 diabetes are overweight)
  • Women and their related genetic, having had transient diabetes during pregnancy (gestational diabetes), or having given birth to children over 4 kg and / or a history suggestive of obstetric diabetic heredity)
  • subjects over 45 years (the incidence of type 2 diabetes increases rapidly after age 45, peaking between 55 and 75).
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The Diagnosis of Diabetes

Monday, March 1st, 2010

Diabetes leads to elevated blood glucose, that is to say the level of sugar in the blood. It is generally abrupt (a few days or weeks) at the onset of type 1 diabetes (T1D) and progressively (several years) on the occurrence of type 2 diabetes (T2DM).

When glucose is frankly high, entailing heavy urine, thirst, fatigue . but when it is not really high there was no fatigue, no thirst, no urine abundant. However, any abnormal rise in blood sugar damages the arteries and nerves, which is responsible for the establishment of complications gradually and without symptoms.

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Diabetes Mellitus Information

Friday, February 19th, 2010

Diabetes Mellitus in the Elderly keeps you up-to-date with the latest information concerning the treatment and understanding of conditions that lead to diabetes mellitus. Discussing the multi-organ involvement of this disease and the contingencies of a wholly effective treatment, this book explains both positive and negative attributes and reactions to tested methods. From Diabetes Mellitus in the Elderly, you’ll receive current facts and data that will help you offer the best care to the growing number of elderly patients afflicted with this disorder.

Offering you a review of studies relating to various aspects of the disease, Diabetes Mellitus in the Elderly discusses innovative information that will assist you in your practice, including:

  • genetic and polygenic links to type 2 diabetes mellitus (2 DM)
  • studies indicating the correlation between increased visceral body fat and old age and hyperinsulinemia, impaired glucose tolerance (IGT), and diabetes mellitus
  • mechanisms that increase the risk of diabetes, such as insulin resistance involving skeletal muscle and malfunctioning of the liver and B-cells from the pancreas that disrupt glucose homeostasis
  • data supporting the importance of strict glycemic control, goals of glycemic control, choice of oral agents, insulin regiments, and oral agent/insulin therapy combinations in the elderly
  • effectiveness and performance of insulin products, such as sulfonylureas, alpha-glucosidase inhibitors, biguanides, and thiozolidinediones
  • European studies that show acarbose may reduce glycemic fluctuations, insulin dosage, and episodes of nocturnal hypoglycemia

Much of the data examined in this book offers you and your colleagues ideas for future research and contains implications for more effective treatments. Complete with charts, tables, and graphs, Diabetes Mellitus in the Elderly will inform you of new developments in the field and help you decide upon the most effective methods of treatment for your patients.

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Recent Research to Prevent Diabtes

Thursday, February 18th, 2010

Current research

  • A preventive approaches tested consists of administering small doses of insulin in people at risk. Although the preliminary results of these tests are very encouraging, experts say it is too early to abandon this track and it is better to wait until research on the subject to draw conclusions définitives
  • Researchers are currently working to develop a vaccine to prevent diabetes type 1. This vaccine prevents the immune system to destroy cells in the pancreas responsible for insulin production. A new research center has been established for this purpose in Australia.
  • Some experts recommend breastfeeding for at-risk children and some believe it should be avoided cow’s milk in these cases (see “Milk Cow” in the section Risk Factors)
  • It is possible that supplementation of vitamin B3 helps prevent the development of type 1 diabetes. The results of several studies conducted between 1987 and 1998, however, contradict this sujet12-15. A meta-analysis published in 1996 and on ten studies (only five double-blind placebo) indicates that treatment of niacinamide may help delay onset of type 1 diabetes by preventing the destruction of beta cells that produce the ‘insulin in the pancréas16. However, several trials analyzed were small (ten studies, 211 subjects in total) and the quality of their methodology.
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Diabetes Type 1

Monday, February 15th, 2010

The Type 1 diabetes affects approximately 10% of all diabetics. This form of the disease can occur at any age but most often it appears in childhood or early adulthood, hence its old name of “juvenile diabetes“.

Diabetes can develop asymptomatic manner over a long period. Individuals who have it produce very little or no insulin due to an autoimmune reaction that destroys partially or fully pancreatic beta cells. The latter role is to synthesize the hormone, which is essential to the use of blood glucose by the body as an energy source. In this type of diabetes, it is absolutely necessary to take regular insulin, hence the name often ascribed to “diabetes mellitus (IDDM).

It is not known precisely what causes the immune system to respond to beta cells. Researchers believe that genetic predisposition and factors related to the environment contribute to the development of type 1 diabetes. We know in particular that certain viruses and toxins can trigger such a reaction in people with genetic predispositions.

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